The journal of allergy and clinical immunology. In practice
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J Allergy Clin Immunol Pract · Sep 2020
Multicenter StudyProspective, Single-Arm, Longitudinal Study of Biomarkers in Real-World Patients with Severe Asthma.
ARIETTA was a prospective, single-arm, noninterventional, multicenter study in patients with severe asthma. ⋯ No prognostic value for serum periostin related to exacerbations was detected. Higher blood eosinophils combined with increased FeNO were potentially associated with increased exacerbation rates.
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J Allergy Clin Immunol Pract · Sep 2020
SARS-CoV-2 Pneumonia in Hospitalized Asthmatic Patients Did Not Induce Severe Exacerbation.
Viral infections are known to exacerbate asthma in adults. Previous studies have found few patients with asthma among severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pneumonia cases. However, the relationship between SARS-CoV-2 infection and severe asthma exacerbation is not known. ⋯ Our results demonstrate that patients with asthma appeared not to be at risk for severe SARS-CoV-2 pneumonia. Moreover, SARS-CoV-2 pneumonia did not induce severe asthma exacerbation.
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J Allergy Clin Immunol Pract · Jul 2020
Prehospital Treatment and Emergency Department Outcomes in Young Children with Food Allergy.
Studies assessing food-induced allergic reactions and prehospital treatments in infants and young children are scarce. ⋯ Infants treated in the ED for FA reactions presented differently than older children. Most infants presented after first-known ingestion of offending foods. Overall, ED epinephrine use was low necessitating additional education to recognize and treat anaphylaxis in the ED.
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J Allergy Clin Immunol Pract · Jun 2020
ReviewClinician Wellness During the COVID-19 Pandemic: Extraordinary Times and Unusual Challenges for the Allergist/Immunologist.
The global spread of coronavirus disease 2019 (COVID-19) has caused sudden and dramatic societal changes. The allergy/immunology community has quickly responded by mobilizing practice adjustments and embracing new paradigms of care to protect patients and staff from severe acute respiratory syndrome coronavirus 2 exposure. Social distancing is key to slowing contagion but adds to complexity of care and increases isolation and anxiety. ⋯ Realizing early warning signs of anxiety, depression, substance abuse, and posttraumatic stress disorder is important to access safe and confidential resources. Implementing wellness strategies can improve flexibility, resilience, and outlook. Historical parallels demonstrate that perseverance is as inevitable as pandemics and that we need not navigate this unprecedented time alone.