Prescrire international
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Prescrire international · Sep 2012
ReviewYaws, a non-venereal treponemal infection. Still endemic in some parts of the world.
Yaws is an infection that mainly affects the poorest populations living in humid tropical areas. We reviewed the literature on yaws, the most common non-venereal treponemal infection, using the standard Prescrire methodology. Yaws is often transmitted directly from person to person. ⋯ Curative treatment consists of a single injection of benzathine benzylpenicillin. The results of a randomised trial suggest that a single oral dose of azithromycin is as effective as penicillin. In India, yaws was successfully eradicated through a programme based on providing information to the population at risk, screening and treatment.
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In a trial including 4065 men aged 16 to 26 years, HPV 6, 11, 16, 18 vaccination reduced the incidence of anogenital warts, but the preventive effect on cancer remains to be demonstrated.
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Prescrire international · Sep 2012
Phentermine: an appetite-suppressant amphetamine classified as a narcotic in France. Is a combination with topiramate on the horizon?
In France, extra restrictions have been placed on this appetite-suppressant drug. Phentermine is widely used in many countries despite its multiple adverse effects and lack of proven efficacy in preventing complications of obesity.