Asian spine journal
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Asian spine journal · Oct 2014
Up-Regulation of Pain Behavior and Glial Activity in the Spinal Cord after Compression and Application of Nucleus Pulposus onto the Sciatic Nerve in Rats.
Experimental animal study. ⋯ Nerve compression with NP application produces pain-related behavior, and up-regulates astrocytes and microglia in the spinal dorsal horn, suggesting that these glia may be related to pain transmission.
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Asian spine journal · Oct 2014
Evaluation of behavior and expression of receptor activator of nuclear factor-kappa B ligand in dorsal root Ganglia after sciatic nerve compression and application of nucleus pulposus in rats.
Experimental animal study. ⋯ The exposure of sciatic nerves to mechanical compression and NP produces pain-related behavior and up-regulation of RANKL in DRG neurons. RANKL may play an important role in mediating pain after sciatic nerve injury with exposure to NP.
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Asian spine journal · Aug 2014
The effect of intravenous paracetamol on postoperative pain after lumbar discectomy.
A randomized, double-blinded controlled trial. ⋯ Intravenous paracetamol as a non-opioid analgesic can relieve postoperative pain in patients undergoing lumbar discectomy; however, its use alone may not represent the best regimen for reducing the needed dose of opioids after operation.
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Retrospective analysis. ⋯ Trials of mini-open lateral approach would be helpful before the trial of XLIF or DLIF. However, special attention is required for complications such as transient lumbosacral plexus palsy.
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Asian spine journal · Aug 2014
Usefulness of Contralateral Indirect Decompression through Minimally Invasive Unilateral Transforaminal Lumbar Interbody Fusion.
Retrospective study. ⋯ Satisfactory results were acquired with MI-TLIF conducted through the unilateral approach of contralateral indirect decompression, in alignment with the bilateral approach. Therefore, contralateral indirect decompression is thought to be a useful procedure in reducing the operation time and volume of blood loss.