Yonsei medical journal
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Yonsei medical journal · May 2015
The utility of three screening questionnaires for obstructive sleep apnea in a sleep clinic setting.
The aim of this study was to determine the diagnostic value of three screening questionnaires in identifying Korean patients at high risk for obstructive sleep apnea (OSA) in a sleep clinic setting in Korea. ⋯ The STOP-Bang questionnaire may be useful for screening OSA in a sleep clinic setting, but its specificity is lower than the acceptable level for this purpose. A new screening questionnaire with a high sensitivity and acceptable specificity is therefore needed in a sleep clinic setting.
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Yonsei medical journal · May 2015
Mean platelet volume is elevated in patients with psoriasis vulgaris.
This retrospective study was done to investigate the mean platelet volume (MPV) level in patients with psoriasis vulgaris and its relationship with disease severity. ⋯ We have shown that MPV is increased in psoriasis patients and correlates with disease severity. Therefore, MPV levels may be considered as a marker of disease severity of psoriasis.
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Yonsei medical journal · May 2015
Detection of plasma BRAF(V600E) mutation is associated with lung metastasis in papillary thyroid carcinomas.
The BRAF(V600E) mutation represents a novel indicator of the progression and aggressiveness of papillary thyroid carcinoma (PTC). The purpose of this study was to determine the clinical significance of free circulating mutant BRAF(V600E) in predicting the advanced disease of PTC. ⋯ These findings suggest that the BRAF(V600E) mutation can be detected using a PNA clamp real-time PCR in the blood of PTC patients with lung metastasis. Future studies are warranted to determine clinical significance of serum BRAF(V600E) mutation in large prospective studies.
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Yonsei medical journal · May 2015
Comparative StudyFirst metatarsal proximal opening wedge osteotomy for correction of hallux valgus deformity: comparison of straight versus oblique osteotomy.
The aim of this study was to compare clinical and radiographic outcomes of proximal opening wedge osteotomy using a straight versus oblique osteotomy. ⋯ Compared with a straight first metatarsal osteotomy, an oblique first metatarsal osteotomy yielded better clinical and radiological outcomes.
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Yonsei medical journal · May 2015
Stimulating effect of a novel synthesized sulfonamido-based gallate ZXHA-TC on primary osteoblasts.
This study is intended to investigate the effects of plants or plant-derived antioxidants on prevention of osteoporosis through the maintenance of reactive oxygen species (ROS) at a favorable level. ⋯ This study may hold promise for the development of a novel agent for the treatment of osteoporosis.