Yonsei medical journal
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Yonsei medical journal · Jan 2014
Application of array-based comparative genomic hybridization to pediatric neurologic diseases.
Array comparative genomic hybridization (array-CGH) is a technique used to analyze quantitative increase or decrease of chromosomes by competitive DNA hybridization of patients and controls. This study aimed to evaluate the benefits and yield of array-CGH in comparison with conventional karyotyping in pediatric neurology patients. ⋯ Although there were relatively small number of tests in patients with pediatric neurologic disease, this study demonstrated that array-CGH is a very useful tool for clinical diagnosis of unknown genome abnormalities performed in pediatric neurology clinics.
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Yonsei medical journal · Jan 2014
Concomitant impact of high-sensitivity C-reactive protein and renal dysfunction in patients with acute myocardial infarction.
The present study aimed to investigate the impact of high-sensitivity C-reactive protein (hs-CRP) and renal dysfunction on clinical outcomes in acute myocardial infarction (AMI) patients. ⋯ High hs-CRP, especially in association with renal dysfunction, is related to the occurrence of composite MACE, and indicates poor prognosis in AMI patients.
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Yonsei medical journal · Jan 2014
The effect of obturator nerve block on hip lateralization in low functioning children with spastic cerebral palsy.
Hip adductor spasticity has a great impact on developing hip displacement in children with cerebral palsy (CP). Obturator nerve (ON) block is less invasive intervention rather than soft tissue surgery for reduction of hip adductor spasticity. The aim of this study is to investigate the effect of ON block on hip lateralization in low functioning children with spastic CP. ⋯ ON block with ethyl alcohol is useful as an early effective procedure against progressive hip displacement in these children with spastic CP.
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Yonsei medical journal · Jan 2014
The assessment of the oncological safety margin of insufficient lymph node dissection in pT2 (pm) gastric cancer.
To identify the effect of insufficient lymph node dissection (LND) on the survival of patients with pT2 gastric cancer. ⋯ If a patient has pN0 or pN1 category after insufficient LND for pT2 gastric cancer, the surgery can be regarded as secure. However, for patients with pN2 or pN3 category, more careful examination is required.
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Yonsei medical journal · Jan 2014
Effect of peritoneal dialysis modality on the 1-year rate of decline of residual renal function.
The effect of different peritoneal dialysis (PD) modalities on the decline in residual renal function (RRF) is unclear due to inconsistencies among studies. In particular, the effect of automated peritoneal dialysis (APD) modalities [continuous cyclic peritoneal dialysis (CCPD) and nightly intermittent peritoneal dialysis (NIPD)] on RRF has not been examined in a large cohort. ⋯ Our results suggest that CAPD might be more helpful than APD for preserving RRF during the first year of dialysis therapy, although there was no significant difference in the 1-year rate of decline of RRF between the two APD modalities.