Yonsei medical journal
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Yonsei medical journal · Jul 2013
Meta AnalysisAssociation of Helicobacter pylori with elevated blood ammonia levels in cirrhotic patients: a meta-analysis.
The association between Helicobacter pylori (H. pylori) and blood ammonia levels in cirrhotic patients is controversial. We aimed to clarify this controvercy by performing a meta-analysis of published studies. ⋯ H. pylori infection is associated with elevated blood ammonia levels in cirrhotic patients, and more large scale studies and stratify analysis are warranted in order to further evaluate this association.
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Yonsei medical journal · Jul 2013
Establishment and evaluation of a simplified evaluation system of acute respiratory distress syndrome.
In recent years, a variety of acute respiratory distress syndrome (ARDS) evaluation systems have been developed worldwide; however, they are not so convenient for the doctors clinically, we decided to establish and evaluate a simplified evaluation system of ARDS (SESARDS). ⋯ SESARDS was shown to be simple, accurate and effective in predicting ARDS progression.
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Yonsei medical journal · Jul 2013
Observational StudyAcute kidney injury in patients with sepsis and septic shock: risk factors and clinical outcomes.
The aim of this study was to investigate clinical characteristics and risk factors of acute kidney injury (AKI) in patients with sepsis and septic shock. Additionally, we explored whether the severity of AKI affects on the clinical outcomes. ⋯ The development of septic AKI was associated with poor clinical outcomes. Furthermore, the severity of AKI was associated with increased mortality.
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Yonsei medical journal · Jul 2013
Case ReportsNovel mutations in the UNC13D gene carried by a Chinese neonate with hemophagocytic lymphohistiocytosis.
Hemophagocytic lymphohistiocytosis (HLH) in different ethnicities has been described in the literature, but few cases in patients of Chinese descent have been reported. Here, we describe the case of a Chinese neonate presenting with HLH carrying novel, compound heterozygous mutations of the UNC13D gene, including [c.2295_2298delGCAG, p. ⋯ Cytokine profile analyses were performed in this patient, and the results were consistent with our previous findings in HLH patients. Cytokine profile monitoring may be helpful in differentiating among various clinical phases of HLH.
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Yonsei medical journal · Jul 2013
Observational StudyPosterior ligamentous complex injuries are related to fracture severity and neurological damage in patients with acute thoracic and lumbar burst fractures.
The proposed the thoracolumbar injury classification system (TLICS) for thoracolumbar injury cites the integrity of the posterior ligamentous complex (PLC). However, no report has elucidated the severity of damage in thoracic and lumbar injury with classification schemes by presence of the PLC injury. The purpose of this study was to accurately assess the severity of damage in thoracic and lumbar burst fractures with the PLC injuries. ⋯ The presence of PLC injury significantly influenced the severity of damage. In management of thoracic lumbar burst fractures, evaluation of PLC injury is important to accurately assess the severity of damage.