Arkhiv patologii
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Examination of 15 autopsies of puerperas who died in the first postpartum days has identified the pathomorphological and immunohistochemical signs differentiating labor sepsis from the other type - postpartum sepsis. Labor sepsis that runs typically of a systemic inflammatory reaction is characterized by initial antenatal inflammation of the fetal membranes and placenta with the latter's immunoimaging of granulocytes, macrophages, plasma cells, and tumor necrosis factor. ⋯ The relative intact pattern of the uterine endo- and myometrium is retained with generalization of an inflammatory reaction along the organs. The pathologist who analyzes female pyoinflammatory diseases in the postpartum period should meticulously investigate all placental components in addition to a puerpera's organs.
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Morphological and morphometric studies have shown that secondary pulmonary hypertension is characterized by more pronounced pathological changes in the pulmonary arterial branches in severe chronic obstructive lung disease (COLD) than in idiopathic fibrosing alveolitis. Secondary pulmonary hypertension does develop in atopic bronchial asthma. Moreover, there are more significant pathological changes in the pulmonary arteries than in the bronchial ones. In severe COLD, the development of emphysema affects that of pulmonary arterial hypertension.
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This two-part review addresses the current diagnostic approaches towards primary cutaneous lymphomas. In this part, main T and NK-cell lymphomas are described with reference to clinical presentation, histological and immunohistochemical features, and genetic alterations based on the new WHO-EORTC classification of cutaneous lymphomas.
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According to the order of the Ministry of Health and Social Development, Professor O. D. Mishnev is appointed principal pathologist of the Ministry. ⋯ It is necessary to set up a federal organizational-and-methodical center for postmortem studies under the Ministry of Health and Social Development. The chief results of the activities of postmortem services of Russia and federal districts over 6 years (2000-2005) are presented. The shortcomings and trends of postmortem services of the country are outlined.
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The authors propose to put the 1991 US Consensus Conference criteria for sepsis into practice and research methodology. This will be helpful in reaching the consensus in definitions.