Oral surgery, oral medicine, and oral pathology
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Oral Surg. Oral Med. Oral Pathol. · Jan 1984
The asplenic patient: a consideration for antimicrobial prophylaxis.
Removal of the spleen predisposes the patient to the development of overwhelming sepsis without a primary site of infection. Transient, usually asymptomatic, bacteremias occur in a wide variety of dental manipulations, particularly those involving the mucous membranes. Occasionally these bacteremias can give rise to serious complications in susceptible patients. A prophylactic preoperative and postoperative antimicrobial regimen is presented for asplenic patients undergoing bacteremia-causing dental treatment.
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Idiopathic myelofibrosis is a hematologic myeloproliferative disorder characterized by progressive marrow fibrosis, extramedullary hematopoiesis, and a leukoerythroblastic anemia. Consequently there are frequent secondarily precipitated multiple systems problems. This is the first report of this entity presenting with orofacial findings. The histopathogenesis, clinical presentation, and the therapeutic goals of treatment are reviewed.
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Oral Surg. Oral Med. Oral Pathol. · Jun 1983
Case ReportsChronic autoimmune thrombocytopenic purpura. A 3-year study.
Idiopathic (autoimmune) thrombocytopenic purpura (ATP) is accepted to be a disorder resulting from accelerated platelet destruction attributed to an autoimmune process. The patient whose case is presented in this article was first seen by a dentist. The oral findings have been documented as the case was followed for 3 years through acute exacerbations, pregnancy, and delivery of an infant with thrombocytopenia. The patient was managed with intermittent steroid therapy and splenectomy.