Akusherstvo i ginekologii͡a
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Akush Ginekol (Sofiia) · Jan 2003
Comparative Study Clinical Trial Controlled Clinical Trial[Cytotec: an effective drug for the induction of labor].
Our purpose was to compare the safety and efficacy of intravaginal Cytotec versus Oxytocin for induction of labor. ⋯ Intravaginal administration of Cytotec appears to be as effective as Oxytocin labor induction.
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The new tendency in used transfusion practice in surgery treat the problem of blood loss and its supplementation with minimal transfusion risk. Transmissive infections and immune complication after blood transfusion are still actual today. The autotransfusion is reasonal alternative in modern transfusion therapy.
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Akush Ginekol (Sofiia) · Jan 2003
Case Reports[Using recombinant activated coagulation factor VII (NovoSeven) in obstetrics].
The authors share their experience about the application of the NovoSeven in four cases with different types of hemostasiologic disturbances. The possibilities for its use in obstetrics and gynecology are discussed.
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Akush Ginekol (Sofiia) · Jan 2003
[Pathology of the endometrium in breast cancer patients treated with tamoxifen (nolvadex)].
The objectives of this study were to: 1) characterize histologically endometrial biopsy findings for genital bleeding in breast cancer patients receiving Tamoxifen; 2) analyze histologically endometrial carcinoma in the same patients. We analyzed biopsy specimens divided into three groups: 1) 112 biopsies (curettages and hysterectomy specimens) from 88 breast cancer patients receiving Tamoxifen (Nolvadex): T+; 2) 27 biopsies (curettages and hysterectomy specimens) from 22 breast cancer patients not receiving Tamoxifen but biopsied for genital bleeding: T-; 3) 139 curettages control samples received for analysis in the period January-March 2000 from women with peri- and postmenopausal genital bleeding: K. The analysis was performed on archival H&E sections. ⋯ Compared with the other two groups (T- and K) the frequency of this finding was statistically significant. No difference was found in the prevalence of endometrial cancer between the three groups. The analyzed endometrial carcinomas in Tamoxifen-treated breast cancer patients show signs, characteristic of Bochman type I: predominantly endometrioid, of low grade and FIGO stage, with good prognosis.