Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica
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Zhongguo Zhong Yao Za Zhi · Sep 2008
[Quantitative analysis of two major secoiridoid glucosides in fruits of Ligustrum lucidum].
To develop an HPLC method for determination of two major secoiridoid glucosides (nuezhenoside and G13) from Fructus Ligustri Lucidi. and determinae nuezhenoside and G13 in samples from different acquisition times and different places. ⋯ The established method can be used to determine two major secoiridoid glucosides (nuezhenoside and G13) in Fructus Ligustri Lucidi simultaneously. Meanwhile it can be used for the quality control of Fructus Ligustri Lucidi.
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Zhongguo Zhong Yao Za Zhi · Jun 2008
[Toxicological assessment on safety of water and 70% ethanolic extracts of nearly ripe fruit of Evodia rutaecarpa].
To study the acute toxicity and mutagenic risk of the water extracts (ERWE) and 70% ethanol extracts (EREE) from the nearly ripe fruit of Evodia rutaecarpa, and provide experimental basis for safety evaluation of ones. ⋯ The oral LD50 of the ERWE and EREE in mice was more than 10.0 g x kg(-1) belonging to non-toxicity on the acute toxicity rating criteria. The both ERWE and EREE showed no genotoxicity in the experimental condition.
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Zhongguo Zhong Yao Za Zhi · Jun 2008
[Adverse drug reactions induced by Mailuoning injection: literature review on 162 cases].
To understand the adverse drug reaction (ADR) induced by Mailuoning injection. 162 ADRs due to the drug were retrieved from national medical journals of 1988-2007 for statistics. It was shown that there was no relationship between ADR and dosage, but ADR appeared mostly in middle-aged and old groups, and more in male than in female. The occurrence of ADR was commonly within 30 min after injection. ⋯ As for the 123 cases of allergy, 38 were anaphylactic shock (accounting for 23.46%), two people died. ADR characterized by immediate type on initial use and tachy type. It should be paid more attention to the Mailuoning injection for the immediate hypersensitivity reaction (such as anaphylactic shock).
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Zhongguo Zhong Yao Za Zhi · Mar 2008
Review[Comparative researches on medicinal property theories of traditional Chinese medicine and traditional Mongolian medicinal herbs].
This article reveals the similarities and differences between the two materia medica systems of traditional Chinese medicine and traditional Mongolian medicine by comparing the medicinal property theories of these two; our expectations are the mutual profits and complementation of the two traditional medicines from each other, a broader clinical use of natural medicinal herbs, and then, a development of traditional medicines.
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Zhongguo Zhong Yao Za Zhi · Mar 2008
[Necessity of applying pharmacovigilance in post-marketing safety monitoring of traditional Chinese medicine injections].
Traditional Chinese medicine (TCM) injection has become one of the hotspots in the new TCM research and development. The serious adverse drug reactions happened in clinical have arosed attention widely in the whole society. ⋯ This paper elucidated the pharmacovigilance's necessity in the post-marketing safety monitoring of TCM injections, basing on the reason of safety problem of TCM injections and the future developing trend of adverse drug reaction monitoring. Also, this paper introduced the rapid signal detection method of spontaneous reporting system database by data mining technology.