Annals of translational medicine

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• Ann Transl Med · Apr 2020

  Extubation strategies in neuro-intensive care unit patients and associations with outcomes: the ENIO multicentre international observational study.

  Prolonged invasive ventilation is common in patients with severe brain injury. Information on optimal management of extubation and on the use of tracheostomy in these patients is scarce. International guidelines regarding the ventilator liberation and tracheostomy are currently lacking. ⋯ ENIO will be the largest prospective observational study of ventilator liberation and tracheostomy practices in patients with severe brain injury undergoing invasive mechanical ventilation, providing a validated predictive score of successful extubation.

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