Frontiers in pharmacology
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Front Pharmacol
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Frontiers in pharmacology · Jan 2011
Serum Adiponectin is Associated with Adverse Outcomes of Asthma in Men but Not in Women.
Murine studies suggest a beneficial effect of systemic adiponectin on asthma. Our objective was to determine the association between serum adiponectin concentrations and asthma control/severity outcomes in men and women separately. ⋯ Higher serum adiponectin concentrations may be independently associated with adverse clinical outcomes of asthma in men but not in women. If biological effect is confirmed in future studies, modification of systemic adiponectin concentrations may open up newer ways to treat asthma in men.