Wiadomości lekarskie (Warsaw, Poland : 1960)
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94 children with chronic myelocytic leukaemia--CML treated in period 1975-1998 were included in the study. Twenty seven of 60 children were treated with hydroxyurea or busulfan with 6 MP. In 33 children aged 1, 5-17 years IFN (Interferon alfa) was applied at the dose of 3 millions units every second day subcutaneously. Our data showed that IFN alfa could be applied as an alternative treatment in children with CML, who have not a donor for allogenic BMT (bone marrow transplantation).
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Myelosuppression is one of the most common side effects during chemotherapy in children with leukemia and lymphoma. That is why the protection of patients against the acute and chronic toxicity of antineoplastic therapy has become a major concern of oncology centers. Amifostine (Ethyol--Schering-Plough) represents a new adjunct for the management of cancer patients receiving chemotherapy. ⋯ Because solid tumors tend to be hypovascular and more acid than normal tissue, amifostine may protect selectively normal tissue. Amifostine is believed to scavenge free radicals, repair radicals on essential molecules and from mixed disulfides to protect normal cells. In this trial we demonstrate how amifostine protects granulocytes, erythrocytes and platelets against toxicity of chemotherapy.
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The authors describe in the article etiology, histopathological features, clinical picture and diagnostics of endogenous and exogenous lipoid pneumonia. The advantages of broncho-alveolar fluid examination and computed tomography in the diagnostics were emphasized.
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In understanding and treatment of tension type headache the psychological stress is considered as one of the most important factors causing and strengthening headache. The aim of this work was the assessment of personality traits in patients suffering from tension-type headache. ⋯ Special personality traits conditioning/characterising tension-type headache were not confirmed. Patients with tension-type headache comparing to subjects from the control group showed neurotism and introversion.
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The application of novel investigative techniques has contributed to an increased understanding of the prevalence, pathophysiology and treatment of disordered gastric motility in diabetes. Abnormal gastric emptying, particularly delayed emptying, occurs frequently and the rate of gastric emptying is influenced by the blood glucose concentration. Disordered gastric motility is likely to be responsible for most upper gastrointestinal symptoms in diabetic patients, but the mechanisms by which abnormal motility leads to symptoms are poorly understood. It appears probable that abnormal gastric emptying contributes to poor glycaemic control.