The American journal of gastroenterology
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Am. J. Gastroenterol. · Feb 2002
Randomized Controlled Trial Comparative Study Clinical TrialConservative treatment of primary gastric low-grade B-cell lymphoma of mucosa-associated lymphoid tissue: predictive factors of response and outcome.
Primary gastric low-grade B-cell lymphoma of mucosa-associated lymphoid tissue may regress with conservative treatment such as anti-Helicobacterpylori therapy or monochemotherapy. The aims of the present study were to analyze the predictive factors of response to anti-H. pylori treatment, to assess the effects of an adjuvant therapy in responding patients, and to evaluate an alternative therapy in nonresponding patients. ⋯ The major negative predictive factor of the tumoral response to anti-H. pylori treatment in patients with primary gastric low-grade B-cell lymphoma of mucosaassociated lymphoid tissue was the presence of perigastric lymph nodes on endoscopic ultrasonography. In responding patients, remission remained stable, suggesting that adjuvant chemotherapy was not useful. In patients who failed to respond to H. pylori eradication, monochemotherapy with chlorambucil proved to be efficient, but new therapeutic modalities should be evaluated to improve the control of the tumoral process.
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Am. J. Gastroenterol. · Feb 2002
Comparative StudyGastroenterology training and career choices: a prospective longitudinal study of the impact of gender and of managed care.
We aimed to determine if gender differences exist in the selection and training of female and male gastroenterology fellows. ⋯ Alterations in gastroenterology training are needed to attract qualified female applicants. New graduates of both sexes lack practice management education.
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Am. J. Gastroenterol. · Feb 2002
Comparative Study Clinical Trial Controlled Clinical TrialLactoferrin in whole gut lavage fluid as a marker for disease activity in inflammatory bowel disease: comparison with other neutrophil-derived proteins.
We investigated which neutrophil-derived proteins in whole gut lavage fluid (WGLF) most accurately reflect disease activity in inflammatory bowel disease. ⋯ Lactoferrin is the most suitable of these proteins for use as a neutrophil-derived WGLF marker of intestinal inflammation.
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Am. J. Gastroenterol. · Feb 2002
Complementary medicine use in children and young adults with inflammatory bowel disease.
We examined the use of complementary alternative medicine (CAM) in children and young adults with inflammatory bowel disease. ⋯ In our survey over 40% of children with chronic inflammatory bowel disease used complementary medicine in addition to conventional therapies. Parental CAM use and number of adverse effects from conventional therapies were the only independent predictors of CAM use. Some complementary therapies have potential for adverse effects and for drug interactions with conventional treatments. Physicians should take a thorough history of CAM use in children with chronic inflammatory bowel disease.
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Am. J. Gastroenterol. · Feb 2002
Plain abdominal radiographic features are not reliable markers of disease extent in active ulcerative colitis.
The aims of this study were to assess the reliability of the distribution of fecal residue, mucosal irregularity, and colonic wall thickening on plain abdominal x-ray as markers of disease extent assessed by technetium-99 m hexamethylpropylene amine oxine-labeled leukocyte scans in active ulcerative colitis (UC). ⋯ The distribution of fecal residue, irregularity of mucosal edge, and colonic wall thickening on plain abdominal radiography do not provide a reliable guide to disease extent in active UC.