Panminerva medica
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Idiopathic pulmonary fibrosis (IPF) is the most common among idiopathic interstitial pneumonia. Life expectancy is estimated around 3-5 years at diagnosis. No reliable prognostic biomarker has been approved for routinary clinical practice of IPF. The aim of this study is to investigate the potential prognostic value of serum CD59 in a cohort of IPF patients. ⋯ CD59 levels were significantly increased in IPF patients, supporting the existence of epithelial damage in the pathogenesis of disease. Lower values of CD59 were associated with a significantly worse prognosis, suggesting a potential role of CD59 in the prognostic estimation of IPF patients.
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The third phase of the Cardiac Rehabilitation Program (CRP) is a lifelong, maintenance phase beginning 3 to 6 months after the cardiac event. Individualized surveillance and monitoring schedules are established. ⋯ Currently, with the emergence of the COVID-19 pandemic, telerehabilitation and telemonitoring are of great value in this phase. The benefits of phase 3 have been demonstrated with prolonged survival by 1.82 years, at a cost of $ 1773 per year of life saved.
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There is a rising burden of non-communicable disease (NCD), especially cardiovascular diseases (CVD) in the developing nations to an extent that they are sometimes terms as NCD epidemics. If unchecked, these NCD epidemics, can impact the healthcare systems and adversely affect the development of the whole country. While CVD is a matter of concern worldwide, it is even more so in low- and middle-income countries, where the incidence and prevalence of these diseases are much worse than developed countries, owning to their large population. ⋯ Therefore, the primordial prevention must start early in life. High-quality clinical trials have traditionally been mainly focusing on primary and secondary prevention settings. There are some key studies that evaluated the role of diet in primordial setting that were discussed in this review.
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Cardiac rehabilitation (CR) has pioneered using multidisciplinary teams to attend all aspects of a patient's illness with high levels of professionalism and quality, providing individualized treatment, and negotiating any changes in lifestyle and treatment course. Clinical management transfers the management capacity to professionals, thus avoiding any increase in costs and healthcare spending, which can result in quality losses and less social legitimacy. Modern CR has been configured as the most effective comprehensive cardiovascular prevention strategy and given its preventive nature it must be a part of all cardiovascular health-related processes as a sub-process. ⋯ Its improvement allows for better rationalization of resources, reduces costs, and offers safer care focused on the needs of the patient. The definition of the technical competencies of the different professionals (functions of the members of the CR unit) is a necessity both from the point of view of its teaching utility, and from planning and management of health services. For a CR team able to carry out clinical management by the quality and safety processes, it needs members who possess professionalism, leadership, adequate communication, adequate training and knowledge management.