Panminerva medica
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The identification of markers capable of evaluating oocyte quality, its maturation, function, and embryo progression and implantation potential has frequently initiated research interest. However, to date, univocal criteria of oocyte competence do not exist. A major cause of low oocyte quality is evidently advanced maternal age. ⋯ Due to the lack of consistent data for the assessment of oocyte quality and competence, probably oocyte morphology and oocyte maturity remain important indicators to determine oocyte quality. The aim of this review was to provide spherical attributes and evidence on recent and present research on the topic by analyzing the current methods for evaluation of the oocyte quality, and the impact of oocyte quality on reproductive outcomes. Additionally, current limitations of oocyte quality evaluation are highlighted and insights on future research are provided to optimize the selection techniques of oocytes to improve ART outcomes.
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Due to the COVID-19 pandemic, the first lockdown was implemented in Austria for almost 7 weeks. In contrast to many other countries, medical consultations were permitted, either by telemedicine or at doctors' offices. Nevertheless, restrictions related to this lockdown could possibly cause an increased risk of deterioration in health, especially in diabetes. This study aimed to assess the impact of Austria's first lockdown on laboratory and mental parameters in a type-2 diabetes mellitus cohort. ⋯ Lack of movement and staying at home resulted in a significant weight gain and worsening of mental well-being in type-2 diabetes during the first lockdown in Austria. Thanks to regular medical consultations, laboratory parameters remained stable or even improved. Thus, routine health check-ups in mainly elderly type 2 diabetic patients are essential to minimize the deterioration of health conditions during lockdowns.
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Since the first pioneering studies on time-lapse systems (TLSs) for embryo incubation, many things have changed. Two main factors influence the development of modern time-lapse incubators for human in-vitro fertilization (IVF): 1) the switch from traditional cell culture incubators to benchtops incubators, more suitable for human IVF; and 2) the improvement of imaging technology. ⋯ This review aims to describe the history and the different TLSs available in the market, to summarize the research and clinical results obtained by using this technology, and to reflect on how this technology is changing the modern IVF laboratory. The current limitations of TLSs will be also reviewed.