Current opinion in neurology and neurosurgery
The most recent articles from:
Curr Opin Neurol Neurosurg
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Curr Opin Neurol Neurosurg · Apr 1992
ReviewPain mechanisms and the management of neuropathic pain.
The nociceptive system is not fixed, but changes in response to its input and activity. This 'plasticity' comprises dynamic developments of both pro- and antinociceptive processes. Recent advances in the understanding of these processes have important implications for the treatment of persistent neuropathic pain.
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Acute management involves triage, well directed investigation and timely surgical intervention when necessary. All are discussed in this review. Cerebral blood flow (CBF) and flow velocity assessment are among the other investigations mentioned. Other topics include paediatric head injury, cerebrospinal fluid (CSF) fistulae, stab wounds and post-traumatic epilepsy.