Acta anaesthesiologica Sinica
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Acta Anaesthesiol. Sin. · Jun 2001
Comparative StudyHemodynamic changes caused by venous gas embolism in dogs: comparisons among air, carbon dioxide and oxygen.
The volume of a bulky venous air emboli (VAE) can be estimated based on the calibration curve generated by injections of minute amount of air into the right atrium (RA) of dogs. We speculated that in patients similar VAE calibration curves could be generated using CO2 injections. As part of pre-clinical evaluation of the usefulness of CO2 injection, the present study was designed to determine whether injection of CO2 into the RA would cause less hemodynamic changes in dogs as compared with that of air or O2. ⋯ Injections of CO2 in increasing volumes into the RA of dogs caused less hemodynamic changes in comparison with that of air and O2.
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Acta Anaesthesiol. Sin. · Mar 2001
Randomized Controlled Trial Comparative Study Clinical TrialEEG-bispectral index changes with ketamine versus thiamylal induction of anesthesia.
The EEG-Bispectral Index (BIS) is a processed EEG information that has been validated as a means to measure the hypnotic effect of anesthetic drugs. In this study we evaluated the BIS changes in induction of anesthesia with ketamine in comparison with that of thiamylal. ⋯ Ketamine-induced dissociative anesthesia produces persistently elevated BIS index which is different from thiamylal and those reported with other conventional anesthetic agents. The established range of BIS index appears not to be applicable in patients under ketamine anesthesia. Monitoring the depth of ketamine anesthesia remains to be a challenging problem.
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Acta Anaesthesiol. Sin. · Mar 2001
Randomized Controlled Trial Comparative Study Clinical TrialEffects on the bispectral index during elective caesarean section: a comparison of propofol and isoflurane.
Awareness during general anesthesia has been a particular problem during caesarean section. About 7 percent of patients undergoing elective caesarean section have reported dreaming or recall of voices during the procedure. The bispectral index (BIS), a value derived from the electroencephalogram (EEG), has been shown to be useful in monitoring the depth of anesthesia. Supplementation of propofol or isoflurane for maintenance of anesthesia has been shown to effectively reduce the incidence of awareness. However, the effects of propofol or isoflurane on the BIS index have not been fully investigated. We therefore designed this study to compare the effects of isoflurane or propofol supplementation on the BIS index in 24 healthy parturients undergoing elective caesarean section. ⋯ We therefore concluded that supplementation of isoflurane or propofol for maintenance of anesthesia can satisfactorily decrease the BIS index and minimize the incidence of awareness in patients undergoing caesarean section under general anesthesia. The BIS index is a reliable monitor of the hypnotic component of anesthesia.
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Acta Anaesthesiol. Sin. · Mar 2001
Randomized Controlled Trial Clinical TrialEffectiveness and safety of rocuronium-hypnotic sequence for rapid-sequence induction.
Either succinylcholine or rocuronium administered after a hypnotic is the current technique for rapid-sequence induction. It is assumed that rocuronium administered before a hypnotic (Rocuronium-hypnotic sequence) may equally provide an acceptable intubation condition as well as a shorter period of apnea in rapid-sequence induction. We designed a prospective, randomized study to evaluate the effectiveness and safety of the technique in a similar rapid-sequence induction. ⋯ Compared with traditional hypnotic-rocuronium or hypnotic-succinylcholine sequence, rocuronium (0.6 mg)-thiopental sequence can provide a similar intubation condition but cause a much shorter apneal period in rapid-sequence induction. In carrying out recuronium-thiopental sequence induction, maintaining a patent infusion line is essential to avoid drug precipitation and awareness of muscular weakness as a result of ill-timed action of thiopental.
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Acta Anaesthesiol. Sin. · Mar 2001
Prolonged interference of patent blue on pulse oximetry readings.
We evaluated the effect of intra-arterial injection of Patent Blue (PB) on pulse oximetry. ⋯ Intra-arterial administration of PB interferes with pulse oximetry readings and the effect lasts for a variable duration. The extent of desaturation may be related to the total accumulative dosage of intra-arterial PB injected.