Clinical orthopaedics and related research
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Clin. Orthop. Relat. Res. · May 2004
Comparative StudyRisk factors for pulmonary emboli after total hip or knee arthroplasty.
Because it is difficult to predict which patients may sustain a pulmonary embolism after total hip or knee arthroplasty, we assessed multiple thrombophilic and hypofibrinolytic parameters to identify risk factors. Twenty-nine patients who survived a known pulmonary embolism after total knee or total hip arthroplasty were matched by age, gender, race, arthritic diagnosis, procedure, and surgery date with 29 patient-controls who had a total hip or knee arthroplasty but who did not have a symptomatic known pulmonary embolism or deep vein thrombosis. Twenty-one serologic measures and five genes associated with thrombophilia, hypofibrinolysis, or both were assessed without knowledge of group assignment. ⋯ Preoperatively, to identify patients at high risk of pulmonary embolism, plasminogen activator inhibitor activity, dilute Russell's viper venom time, prothrombin time, and cholesterol levels were most predictive. Using at least one abnormality of these four measures as a screening test to detect risk of pulmonary embolism, the test is sensitive (100%), and the predictive value of a negative test is high (100%). After additional prospective study, this may allow identification of patients at low risk (the majority of patients) in whom anticoagulation may not be required and a small group of patients at high risk for pulmonary embolism in whom prophylactic anticoagulation should be provided.
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Clin. Orthop. Relat. Res. · May 2004
Review Comparative StudyThe treatment of fractures of the femur in patients with head injuries. 1973.
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Clin. Orthop. Relat. Res. · May 2004
Review Comparative StudyAcute knee dislocations and their complications. 1969.
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Clin. Orthop. Relat. Res. · May 2004
Review Comparative StudyTreatment of the mangled lower extremity after a terrorist blast injury.
Terrorist bombings, with resultant blast injuries, have been increasing in frequency during the past 30 years. Injury to the musculoskeletal system is common in victims who survive such attacks. Substantial injury to the limbs may occur through several different mechanisms, each of which may affect prognosis and alter the treatment algorithm. ⋯ This management protocol may improve the medical facility's ability to manage system resources while treating patients with severe blast injuries. The decision of whether to salvage or proceed with limb amputation is one of the most difficult in orthopaedic trauma. A basic education in the mechanisms of blast damage, a methodical approach to resuscitation, and mangled extremity treatment, likely can improve surgical success.
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Clin. Orthop. Relat. Res. · May 2004
Review Comparative StudyPulmonary aspects of treatment of long bone fractures in the polytrauma patient.
During the past decade, there have been significant advances in the treatment of long bone fractures in the polytraumatized patient. The major controversy in this area is whether definitive long bone stabilization needs to be done emergently. ⋯ The major benefits of fixation are: (1). improve mobilization to enhance pulmonary function; (2). decreased narcotic requirements with improved pain control after fixation; and (3). early aggressive fluid resuscitation associated with operative intervention. Patients with multisystem injury who are underresuscitated or are unstable should have early external fixation because temporizing skeletal stabilization until definitive fixation can be done.