Clinical orthopaedics and related research
-
Clin. Orthop. Relat. Res. · May 2015
rhPDGF-BB promotes early healing in a rat rotator cuff repair model.
Tendon-bone healing after rotator cuff repair occurs by fibrovascular scar tissue formation, which is weaker than a normal tendon-bone insertion site. Growth factors play a role in tissue formation and have the potential to augment soft tissue healing in the perioperative period. ⋯ Augmenting the healing environment to improve the structural integrity and to reduce the retear rate after rotator cuff repair may be realized with continued understanding and optimization of growth factor delivery systems.
-
Clin. Orthop. Relat. Res. · May 2015
Randomized Controlled Trial Comparative StudyAntegrade intramedullary pinning versus retrograde intramedullary pinning for displaced fifth metacarpal neck fractures.
Severe angulation or shortening can be a surgical indication for fifth metacarpal neck fracture. In a previous meta-analysis, antegrade intramedullary pinning was shown to produce better hand function outcomes than percutaneous transverse pinning or miniplate fixation for treatment of fifth metacarpal neck fractures. However, the outcomes of retrograde intramedullary pinning, to our knowledge, have not been compared with those of antegrade intramedullary pinning. ⋯ Level I, therapeutic study.
-
Clin. Orthop. Relat. Res. · May 2015
Do glycemic markers predict occurrence of complications after total knee arthroplasty in patients with diabetes?
Patients with diabetes have increased risk of infections and wound complications after total knee arthroplasty (TKA). Glycemic markers identifying patients at risk for complications after TKA have not yet been elucidated. ⋯ Level III, prognostic study.