Anaesthesia, critical care & pain medicine
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Anaesth Crit Care Pain Med · Jun 2015
Multicenter Study Observational StudyThe daily cost of ICU patients: A micro-costing study in 23 French Intensive Care Units.
To estimate the daily cost of intensive care unit (ICU) stays via micro-costing. ⋯ The average cost of one day of ICU care in French National Hospitals is strongly correlated with the duration of bedside-care carried out by human resources.
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Anaesth Crit Care Pain Med · Jun 2015
Randomized Controlled Trial Multicenter StudySedative premedication before surgery--A multicentre randomized study versus placebo.
Anxiolytic premedication before non-ambulatory surgery in adult patients may have become of less importance in an era of better preoperative patient information. Moreover, an oral hypnotic given the night before surgery may be as efficient as an anxiolytic for relieving patient anxiety. These two strategies were compared for superiority to a placebo and to each other for non-inferiority. ⋯ Premedication in non-ambulatory surgery is no more effective than a placebo, owing to the very moderate level of anxiety experienced by patients.
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Anaesth Crit Care Pain Med · Jun 2015
One half of patients reports persistent pain three months after orthopaedic surgery.
To determine persistent post-surgical pain prevalence after orthopaedic surgery with its impact on patient quality of life and to assess factors related to it. ⋯ Chronic, post-surgical pain is common after orthopaedic surgery, leading to analgesic consumption and sleep disturbance. Patients at high risk for developing chronic post-surgical pain must be identified preoperatively. The development of postoperative pain clinics should be one way to respond to this public health problem.
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Anaesth Crit Care Pain Med · Jun 2015
Use of aztreonam in association with cefepime for the treatment of nosocomial infections due to multidrug-resistant strains of Pseudomonas aeruginosa to β-lactams in ICU patients: A pilot study.
Resistance to all β-lactams is emerging among Pseudomonas aeruginosa (PA) clinical isolates. Aztreonam and cefepime act synergistically in vitro against AmpC overproducing PA isolates. The objective of this study was to evaluate the clinical efficacy of this treatment in ICU patients infected with multidrug-resistant PA. ⋯ These data suggest that the association of cefepime plus aztreonam could be an attractive alternative in the treatment of infections with multidrug-resistant PA to all β-lactams with a clinical efficacy rate of 69%.
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Anaesth Crit Care Pain Med · Jun 2015
Novel CO2 removal device driven by a renal-replacement system without hemofilter. A first step experimental validation.
To study the technical effectiveness of a novel extracorporeal CO2 removal device in removing CO2 from blood. ⋯ A device based on a Prismaflex(®) platform was technically effective in removing CO2 from the blood, thus decreasing PaCO2 and acidosis in hypercapnic pigs.