Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition
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Sichuan Da Xue Xue Bao Yi Xue Ban · Mar 2020
Review[Biological Product Development Strategies for Prevention and Treatment of Coronavirus Disease 2019].
Coronavirus disease 2019 (COVID-19) caused by the novel coronavirus, also known as severe acute respiratory syndrome coronavirus 2 (SARS-Cov-2), has become a Public Health Emergency of International Concern. Due to the large infection population, broad transmissibility and high mortality, it is urgent to find out the efficient and specific methods to prevent and treat COVID-19. ⋯ According to the research advances of severe acute respiratory syndrome (SARS) and Middle East respiratory syndrome (MERS), we reviewed the potential application of biological products such as interferon, convalescent plasma, intestinal micro-ecological regulators, vaccines and therapeutic antibodies, etc. , on prevention and treatment of COVID-19. May this review be helpful for conquering COVID-19 in the near future.
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Sichuan Da Xue Xue Bao Yi Xue Ban · Mar 2020
Case Reports[Clinical Study and CT Findings of a Familial Cluster of Pneumonia with Coronavirus Disease 2019 (COVID-19)].
We studied the epidemiological and clinical data collected from a family with 5 people, in which there were 3 family member diagnosed as coronavirus disease 2019 (COVID-19). We found that the first patient in this family had Wuhan city travel history. Close contact in daily life was the route of infection. ⋯ Characteristic imaging changes were found with grass opacity (GGO), consolidation and septal thickening mainly distributed in peripheral and posterior area by thoracic CT scan in the 3 patients. The abnormality in laborotary test included lower white blood cell count, neutrophil count and lymphocyte count，increasing fibrinogen and C-reactive protein，decreasing myohaemoglobin and increasing lactate dehydrogenase. The epidemiological and clinical features could provide quicker diagnosis and better management for the COVID-19 infected patients.
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Sichuan Da Xue Xue Bao Yi Xue Ban · Dec 2019
[Impact of Air Pollution and Meteorological Factors on Outpatient Visits for Dermatitis: a Time-series Study].
To explore the effect of air pollution and meteorological factors on the outpatient visits. ⋯ Air pollutants may be a risk factor for dermatitis, and relative humidity can reduce the risk of dermatitis.
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Sichuan Da Xue Xue Bao Yi Xue Ban · Jul 2019
[Role of p38 Mitogen-activated Protein Kinase Signaling Pathway in the Hippocampal Neurons Autophagy of Rats with Sepsis].
To investigate the role of p38 mitogen-activated protein kinase (MAPK) signaling pathway in autophagy of neurons in hippocampus of sepsis rats. ⋯ Inhibition of p38 MAPK signaling pathway in sepsis rats can further activate autophagy and protect neurons in the hippocampus.
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Sichuan Da Xue Xue Bao Yi Xue Ban · Sep 2018
[Three-dimensional Ultrasound Imaging of Coronal Curvature and Vertebral Rotation Changes from Supine to Standing in Patients with Adolescent Idiopathic Scoliosis].
To investigate the gravitational effect on coronal curvature and vertebral rotation using 3-D ultrasound in patients with adolescent idiopathic scoliosis (AIS). ⋯ 3-D ultrasound can reveal changes of coronal curvature and vertebral rotation from a supine to a standing posture in patients with AIS, which increase with the severity of AIS. Further studies in large samples are warranted.