Rheumatology
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To investigate the clinical impact of a brief transition programme for young people with JIA. ⋯ Implementation of a transition programme as a brief intervention can improve the perceived health and quality of life of adolescents with JIA during the transition process, as well as the parenting behaviours of their parents. Based on the present study, a randomized controlled trial can be designed to evaluate the effectiveness of the transition programme.
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Letter Review Case Reports
Paradoxical psoriatic arthritis in a patient with psoriasis treated with ustekinumab.
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To study the role of deoxyribonuclease (DNase) I activity and ANCA in propylthiouracil (PTU)-induced lupus-like syndrome (LLS). ⋯ PTU, as a trigger, and low DNase I activity, as a predisposing factor, may lead to LLS. Polyspecific ANCAs are useful markers for differentiating SLE from PTU-induced LLS. Low DNase I activity might be an important prognostic biomarker for PTU-induced LLS. Monitoring of ANCA and DNase I activity may prevent long-lasting exposure to causal drugs, unnecessary immunosuppressive therapy and severe complications of LLS.
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Randomized Controlled Trial
Intravenous neridronate in the treatment of acute painful knee osteoarthritis: a randomized controlled study.
The aim of this randomized, double-blind, placebo-controlled study was to assess the efficacy of i.v. neridronate in controlling pain in patients with acute painful knee OA. ⋯ In patients with acute painful knee OA, four infusions of neridronate are associated with a clinically relevant pain benefit.