Journal of clinical neuromuscular disease
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J Clin Neuromuscul Dis · Dec 2004
Acute onset of deep peroneal neuropathy during a golf game resulting from a ganglion cyst.
We report a case of sudden onset of deep peroneal neuropathy resulting from a ganglion cyst. Electrophysiology demonstrated a severe deep peroneal neuropathy with axonal loss and probably proximal conduction block. ⋯ Surgical resection of the ganglion resulted in gradual improvement of strength. Peroneal nerve ganglia should be considered in the evaluation of patients with sudden painless foot drop.
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This article reviews controversies surrounding the concept of myasthenic crisis. Literature review and our own experience demonstrate that there is disagreement about how a crisis should be defined, what the implications of a crisis are, whether crises are preventable, and how crisis incidence should be calculated. ⋯ We argue that crisis need not "doom" a myasthenic patient to a different prognosis or response to therapy compared with myasthenic patients with severe generalized weakness. Finally, we argue that crisis is preventable and that crisis incidence, calculated in a standardized fashion, could be a useful outcome measure.
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J Clin Neuromuscul Dis · Dec 2001
Gabapentin and venlafaxine for the treatment of painful diabetic neuropathy.
To evaluate the safety and efficacy of gabapentin and venlafaxine in the treatment of painful diabetic neuropathy in patients whose pain did not improve with gabapentin monotherapy. ⋯ (1) Gabapentin is efficacious in the treatment of painful diabetic neuropathy; (2) and (3) in patients who do not respond to gabapentin monotherapy, the addition of venlafaxine is also efficacious.
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A new clinical sign in sarcoglycanopathies is described. Patients with sarcoglycanopathies showed a phase of abduction of the thighs while rising from the ground: the hip abduction sign. ⋯ This sign had a sensitivity of 76.2%, specificity of 98%, and was most conspicuous between 3 and 10 years of disease duration. The hip abduction sign is an important clinical indicator of sarcoglycanopathies.