Clinical intensive care : international journal of critical & coronary care medicine
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Clin Intensive Care · Jan 1995
Subjective psychological status of severely ill patients discharged from mechanical ventilation.
To evaluate psychological status in consecutive survivors of ICU who needed mechanical ventilation (MV). ⋯ These results showed that psychological status is poor in ventilated ICU patients, which should be considered in their care.
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Clin Intensive Care · Jan 1995
Clinical TrialPilot clinical trial of an anti-TNF alpha monoclonal antibody for the treatment of septic shock.
To determine the safety and pharmacokinetics of an anti-tumour necrosis factor (TNF alpha) monoclonal antibody in the treatment of septic shock, and to evaluate the biological evolution of cytokine response. ⋯ No side effects were noted during treatment regardless of the dose used; however, further studies are needed to determine the clinical efficacy of this agent in septic shock.
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The transition from mechanical ventilation to spontaneous breathing in the intensive care unit is a two-stage process: weaning and extubation. Certain parameters require consideration before the commencement of weaning, namely respiratory function (both pulmonary gas exchange and respiratory muscle strength), cardiovascular status, stability of clinical condition, low metabolic demands, psychological factors and, possibly, patient collaboration. Appropriate sedation is crucial for successful weaning to keep the patient rested and to maintain the oxygen consumption and carbon dioxide production low. ⋯ This transition may be considered to comprise two separate stages, namely weaning and extubation. Weaning consists of preparation for spontaneous breathing supported and monitored by a mechanical ventilator and attendant monitoring of all the important vital parameters, while extubation marks the final switch to unsupported spontaneous breathing, which may be quite a big step for the patient. Important weaning parameters.
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Clin Intensive Care · Jan 1994
ReviewA multi-disciplinary approach to families of brain dead children.
To relate our multi-disciplinary approach to families of brain dead children. ⋯ Our multi-disciplinary approach may assist clinicians and other health care providers in successfully dealing with families of brain dead children.