Deutsche medizinische Wochenschrift
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The elderly patient with acute coronary syndrome (ACS) is often not treated on an evidence based basis due to age, previous illnesses and also an increased risk of bleeding. This applies to both drug and interventional therapy. However, valid data clearly show that elderly patients in particular benefit from guideline-adherent therapy, especially interventional revascularisation.
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Dtsch. Med. Wochenschr. · Jan 2021
Historical Article[The early phase of the COVID-19 pandemic in Bavaria, Germany].
The effect of non pharmacological interventions (NPIs) during an epidemic disease outbreak is well accepted dating back to historical events. NPIs involve numerous measurements like hygiene rules or contact restriction that are applied during given situations, while so far only limited quantitative data exist to rate the overall effectiveness. ⋯ To be effective, NPIs need to applied early, if possible even before the beginning of the exponential phase.
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Polypharmacia is a frequent challenge in modern medicine due to increasing complexity of both patients' aspects in an ageing society - multimorbidity - and progress of therapeutic approaches. Although risks are clearly increasing with number of simultaneously prescribed drugs, neither analysis of the polypharmacia-problem solely by number nor focusing on deprescribing strategies by number alone is sufficient. ⋯ Pattern analysis may help this, by identifying both the most vulnerable patients and polypharmacia-pattern with pronounced risk burden. Patient vulnerability depends significantly on functional abilities and prioritizing therapeutic goals in a comprehensive deprescribing process needs to implement stage of life and disease.
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Dtsch. Med. Wochenschr. · Jan 2021
Case Reports[Retrorectal teratoma (dermoid cyst) of an adult - Diagnosis and treatment based on an example of a case report].
A 29 year old woman was introduced to the surgical department with a history of pain in the lower lumbar spine. ⋯ Retrorectal Tumors not associated with the rectum in the small pelvic are rare. These tumors should be surgically removed.
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Diabetic dyslipidemia is a major cause of the increased cardiovascular risk in diabetes. This lipid disorder is characterized by increased plasma triglycerides, increased remnant particles of triglyceride-rich lipoproteins, small dense LDL particles and reduced HDL cholesterol. ⋯ Fibrates and omega-3 fatty acids currently do not play a significant therapeutic role. A consistent and target-oriented therapy of diabetic dyslipidemia is a prerequisite for a cardiovascular risk reduction in patients with diabetes, which has been well proven in clinical studies.