Deutsche medizinische Wochenschrift
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Retinal microvascular function is highly depending on macrovascular circulation and especially on blood pressure variability and nocturnal blood pressure. The eyes are more subject to central hemodynamics compared to peripheral pressures. Pulse wave analysis is essential here and can reveal masked aortic hypertension. ⋯ Early hypertensive changes can be visualized best by laser scanning multi-color devices, and the vessel diameters (AV-Ratio) are measured precisely by static vessel analysis. Functional disorders of vascular motility are delineated reproducibly by devices for dynamic vessel analysis. Also functional effects of cardiovascular therapy measures can be judged by these means: micro- meets macrocirculation.
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Dtsch. Med. Wochenschr. · Jul 2021
[COVID-19: Compulsory vaccination for workers in the medical field?]
Now that the majority of medical personnel have been vaccinated against COVID-19 or are at least willing to be vaccinated, it is necessary to discuss whether employees can be required to be vaccinated. Can employers demand proof of vaccination, and are there consequences under labor law for refusing to vaccinate? Currently, there is no general legal COVID-19 vaccination requirement. Any mandatory vaccination is an encroachment on the fundamental right to physical integrity and to informational self-determination. This encroachment on fundamental rights must be weighed up in each individual case.
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Dtsch. Med. Wochenschr. · Jun 2021
[Diagnosis and treatment of HIV-associated lymphoma: Update 202].
The risk of malignant lymphomas is markedly increased in HIV-infected persons even in the era of effective combination antiretroviral therapy. Major risk factors are the depth of CD4-cell nadir and HIV viremia. R-CHOP remains treatment of choice for diffuse large B-cell lymphoma. ⋯ Favourable results have been reported with a stage adapted treatment for HIV-Hodgkin lymphoma. Patients with relapsed/refractory HIV-lymphoma should undergo autologous stem cell transplantation if indicated. Successful anti-CD19 CAR T-cell therapy was also reported in HIV-infected patients with refractory B-cell lymphoma.