Deutsche medizinische Wochenschrift
-
Dtsch. Med. Wochenschr. · Dec 2023
[Feaver Concepts in the Early Work of Poeta Medicus Friedrich Schiller].
Friedrich Schiller wrote a Latin "Prüfschrift" (thesis) on fever diseases in 1780 as part of his medical studies in Stuttgart. In it, he accuses nature of aggravating inflammation through excessive resistance. ⋯ Accordingly, the descriptions of the two main types of fever in the "Prüfschrift" do not turn out to be "objective" either but contain positive and negative connotations: In a sense, personified heroes and hypocrites are medically juxtaposed and pathologised. In another early poem about the plague (1782), Schiller also interpreted and used fever as an expression of human vitality and natural power, as an anthropological sign for the interconnectedness of soul and body: soul forces are revealed in fever, and the drama of human existence becomes particularly clear in the struggle between nature and disease.
-
Medical views on the value and risks of tobacco use have changed radically over the centuries. In the 16th century, tobacco was introduced to continental Europe as a medicinal plant and quickly rose to become a "cure-all." When hedonistic pipe smoking became widespread in continental Europe during the Thirty Years' War, physicians warned of the consequences of tobacco abuse. For centuries, tobacco herb was now considered both harmful and curative. ⋯ Statistical proof of the direct correlation was provided in the twenties and thirties by Fritz Lickint, among others. In 1939, the Cologne physician Franz Hermann Müller presented the first case-control study on the relationship between smoking and lung carcinoma, which received little international attention. The epidemiological studies published in the 1950s by English and American scientists were based on the same scientific approach as Müller's work but were now considered groundbreaking.
-
Dtsch. Med. Wochenschr. · Nov 2023
[Scoring tool to identify patients at increased risk for drug-related problems: results of a point prevalence study at hospital admission].
Drug therapy is a high-risk process and requires special attention, especially at sectoral borders. Pharmaceutical services such as medication review are appropriate measures to identify drug-related problems and thus improve the safety of drug therapy. Risk-scoring tools have been described in the literature as helpful for prioritizing medication reviews for patients at high risk for drug-related problems. ⋯ Prioritization with the help of a risk-scoring tool is essential as pharmacy services in Saxon hospitals still need to be regularly established and in order to identify patients with an increased risk for drug-related problems at an early stage.
-
Clinically, disorders of lipid metabolism often remain without symptoms. Typical skin lesions, however, can be indicative. Secondary hyperlipoproteinemias (HLP) are more common than primary hyperlipoproteinemias; they can (partially) be improved by treating the underlying disease. ⋯ It is indicated in moderate and high risk of vascular disease, progression of atherosclerosis in "well-controlled" LDL cholesterol, familial clustering of atherosclerosis or high Lp(a), evidence for elevated Lp(a) coming from lipoprotein electrophoresis, aortic stenosis and in patients in whom statins have a poor effect. Genetic diagnostics needs to be considered if primary HLP is suspected. It is most frequently conducted for suspected familial hypercholesterolemia and has already been recommended in guidelines.