Deutsche medizinische Wochenschrift
-
Dtsch. Med. Wochenschr. · Feb 2023
[Clinical and procedural characteristics of patients with acute coronary syndrome during the COVID-19 pandemic 2020 compared to a control group from 2019].
During the COVID-19 pandemic medical treatments including emergencies were often delayed, in part because of fear of an infection with Sars-CoV-2. Even patients with an acute coronary syndrome (ACS) were affected by these circumstances. In the present study we provide a systematic comparison of patients with ACS during the COVID-19 pandemic compared to a control group. ⋯ Despite overall comparable numbers of ACS patients those admitted during the COVID-19 pandemic were more frequently diagnosed with NSTEMI and had a larger extent of coronary disease compared to a control group.
-
Dtsch. Med. Wochenschr. · Feb 2023
[COVID 19 - Hospital Admission in the First and Second Wave in Germany].
We analyzed patients' characteristics and hospital admission in Germany's first and second COVID 19 wave. ⋯ Patients' characteristics did not vary in Germany's first and second COVID 19 wave, but anticoagulation and dexamethasone were applied more frequently in the second wave. In addition, there were fewer thromboembolic complications in the second wave.
-
Dtsch. Med. Wochenschr. · Feb 2023
Case Reports[Cefiderocol in AML patient with neutropenic infection due to 4MRGN Klebsiella pneumoniae (VIM-1)].
The 68-year-old patient presented with fever, general malaise and physical weakness in neutropenia during a known relapse of acute myeloid leukaemia after allogeneic stem cell transplantation. ⋯ 4MRGN pathogens are Gram-negative rod-shaped bacteria that are resistant against four main bactericidal antibiotic groups (Acylureidopenicillins, 3rd generation cephalosporins, carbapenems, and fluoroquinolones) and thus difficult to treat. The present case demonstrates good clinical efficacy for cefiderocol even in pathogens resistant to antibiotics such as colistin and ceftazidime/avibactam and highlights the importance of antibiogram-tailored therapy.
-
Barrett's esophagus has been an important issue in clinical medicine for many years. In the 70 s of the last century, the association between gastroesophageal reflux disease and BE was detected. Only ten years later, the association between BE and adenocarcinoma of the esophagus was reported. ⋯ Only in case of malignant transformation of BE which may range from low-grade dysplasia to high-grade dysplasia and early Barrett's cancer, endoscopic therapy is indicated. At present, there are emerging techniques of artificial intelligence. Due to these rapid developments in BE management, it is important to keep an eye on the current status of BE management.
-
Dtsch. Med. Wochenschr. · Feb 2023
Comment[Neglected differentiations: Of relative and absolute risk reduction and of seat belts and vaccines].
It is often reported that established COVID-19 vaccines have an efficacy of 70 % or more in preventing serious illnesses or deaths. On the other hand, critics claim that the vaccines have actually shown less than 1 % efficacy in studies and are therefore of little use. Which statement is correct? And where do these discrepancies come from?