Deutsche medizinische Wochenschrift
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Dtsch. Med. Wochenschr. · Sep 2022
[Triglycerides - assessment as risk factor and therapeutic goals].
Elevated triglycerides and their lipidological consequences (small, dense LDL, residual particles (remnants), reduced HDL cholesterol) are an important and independent cardiovascular risk factor. Particularly in diabetes mellitus, hypertriglyceridemia is regarded as the main cause of high cardiovascular morbidity and mortality; very high triglyceride levels can cause acute pancreatitis. This article provides an overview of the current scientific status of the pathogenesis and clinical significance of hypertriglyceridemia.
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A 56-year-old male patient consulted our surgical department presenting repetitive pain in his right upper abdomen and already known cholecystolithiasis. There were no other findings in the clinical examination; fever or abnormalities concerning bowel movement or micturition were denied. Except from the extirpation of a melanoma and an appendectomy years ago there were no relevant previous illnesses. ⋯ Gallbladder metastasis of any cancer entities are a rare event, but some studies suggest that the number of events is underestimated concerning the malignant melanoma.If there is a corresponding medical history, symptoms should quickly lead to determined diagnosis and, if in doubt, to cholecystectomy.