The journal of clinical hypertension
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J Clin Hypertens (Greenwich) · Apr 2012
Case Reports Comparative StudyPage kidney: etiology, renal function outcomes and risk for future hypertension.
The initial description of Page kidney, a form of renin-mediated hypertension, included athletes with renal subcapsular hematoma after flank trauma. Subsequently, nontraumatic etiologies were identified. In this study, the authors compare traumatic and nontraumatic causes of Page kidney. ⋯ Trauma patients tended to be younger, male, have less renal impairment and lower systolic blood pressure. Nontrauma patients required more antihypertensive medications and had a higher nephrectomy rate. New-onset hypertension occurred independent of etiology, calling for close surveillance of blood pressures.
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J Clin Hypertens (Greenwich) · Mar 2012
Regular use of a home blood pressure monitor by hypertensive adults--HealthStyles, 2005 and 2008.
The authors analyzed HealthStyles surveys 2005 and 2008 combined to assess the prevalence of regular home blood pressure monitor (HBPM) use among hypertensive adults. All data were self-reported. The authors calculated odds ratios (ORs) of regular HBPM use and relative percent change (RPC) in the use of HBPM between the 2 survey years. ⋯ Non-Hispanic blacks were significantly less likely (OR, 0.69; 95% CI, 0.55-0.86) to be regular HBPM users than non-Hispanic whites. From 2005 to 2008, the RPC in regular HBPM use was 14.2% (from 40.1% to 45.8%); the largest RPCs were for the 3 youngest age groups, men, non-Hispanic blacks, and those with a household income of $40,000 to 59,900. Because HBPM has been demonstrated to aid in hypertension control, health care professionals should promote its use especially among hypertensives who are younger, non-Hispanic blacks, Hispanics, or with a lower income.
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J Clin Hypertens (Greenwich) · Feb 2012
Reviewβ-blockade: benefits beyond blood pressure reduction?
Hypertension is a major cardiovascular (CV) risk factor, but several other common conditions, including chronic obstructive pulmonary disease (COPD), osteoporosis, and peripheral arterial disease (PAD), have been shown to independently increase the risk of CV events and death. The physiological basis for an increased CV risk in those conditions probably lies in the augmentations of oxidative stress, endothelial dysfunction, systemic inflammation, and arterial stiffness, which all are also hallmarks of hypertension. β-Blockers have been used for the treatment of hypertension for more than 40 years, but a number of meta-analyses have demonstrated that treatment with these agents may be associated with an increased risk of CV events and mortality. ⋯ The purpose of this review is to summarize pathophysiologic mechanisms thought to be responsible for the increased CV risk associated with COPD, osteoporosis, and PAD, and examine the possible benefits of vasodilatory β-blockade in those conditions. Our examination focused on nebivolol, a β(1) -selective agent with vasodilatory effects most likely mediated via β(3) activation.