Rivista di neurologia
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Rivista di neurologia · Jul 1990
Review Comparative Study[Alzheimer's disease and Down's syndrome: a review].
In the last few years a number of studies highlighted striking similarities between Alzheimer's Disease and Down's Syndrome. More specifically, neurochemical, pathologic, genetic and clinical features of the Alzheimer's Disease were described also in the Down's Syndrome, but with some particular differences. The most significant literature reports investigating these aspects are reviewed.
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A study of 46 patients has shown that Clonazepam is an effective drug in preventing attacks of pain in essential trigeminal and glossopharyngeal neuralgia and in Sluder's syndrome. The therapeutic action of the drug is less evident in different types of migraine, among which only the combined headache presents good results to the treatment. The effective dose of this drug is generally not greater than 3 mg/die and does not give rise to side effects in long-term prescription.