Medical and pediatric oncology
-
Med. Pediatr. Oncol. · Apr 2001
Review Multicenter StudyLong-acting morphine for pain control in paediatric oncology.
Guidelines for treatment of paediatric cancer pain recommend the usage of long-acting morphine. However, published paediatric experience with this drug is restricted to 147 children not systematically evaluated, and thus insufficient. We aimed to systematically analyse the age-dependent effects and adverse effects of long-acting morphine in paediatric cancer patients. ⋯ In paediatric haematology/oncology, pain control by oral long-acting morphine proved to be safe and effective even in the very young patients. The pharmacological properties of long-acting morphine are ideally suited for paediatric use, combining efficacy and compatibility.
-
Med. Pediatr. Oncol. · Apr 2001
Clinical Trial Controlled Clinical TrialArt therapy as support for children with leukemia during painful procedures.
Children with leukemia undergo painful procedures such as lumbar puncture and bone marrow aspiration. To overcome pain, certain units offer total anesthesia; others offer generic support; others offer no preparation at all. Since September, 1997, we have provided leukemic children with art therapy (AT), a nonverbal and creative modality that develops coping skills. Our goal is to prevent anxiety and fear during painful interventions as well as prolonged emotional distress. ⋯ AT was shown to be a useful intervention that can prevent permanent trauma and support children and parents during intrusive interventions.
-
Med. Pediatr. Oncol. · Apr 2001
Randomized Controlled Trial Comparative Study Clinical TrialRandomized comparison of cefepime versus ceftazidime monotherapy for fever and neutropenia in children with solid tumors.
With the availability of new broad-spectrum antibiotics, initial therapy with a single agent has become an alternative to classic combinations, especially beta-lactam antibiotics plus aminoglycosides, in the management of febrile neutropenic cancer patients. ⋯ CFP is as effective and safe as CFZ for the empirical treatment of febrile episodes in neutropenic patients with solid tumors.
-
Med. Pediatr. Oncol. · Mar 2001
Letter Randomized Controlled Trial Clinical TrialNeoadjuvant chemotherapy in osteosarcoma: the experience at the Hospital Infantil de Mexico from August 1996 to August 1999.
-
Med. Pediatr. Oncol. · Mar 2001
Randomized Controlled Trial Clinical TrialLumbar puncture in pediatric oncology: conscious sedation vs. general anesthesia.
Lumbar punctures (LP) generally have been performed with conscious sedation (CS) but are increasingly performed using general anesthesia (GA) owing to the belief that this is less distressing. The aim of this study was to compare these two methods concerning distress, discomfort, pain, well-being and security after the LP, and problems with the LP. ⋯ Outcomes for CS and GA in LP were similar. Although there were failures with the CS model, most preferred it to GA. LP in CS also saved time and medical resources. An alternative approach would be to have a pediatric anesthesiologist available at the oncology ward for these elective LPs to provide the sedation or anesthesia required by each individual.