Hospital practice (Office ed.)
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Hosp. Pract. (Off. Ed.) · Jun 1993
ReviewOutpatient parenteral antibiotic therapy. Management of serious infections. Part I: Medical, socioeconomic, and legal issues. Advances in i.v. delivery.
Physicians who prescribe outpatient parenteral antibiotic therapy must remain abreast of advances in intravenous catheters and infusion pumps so they can select equipment that realizes the full potential of therapy and suits the patient's needs for comfort, reliability, and safety. The cost of equipment and installation can vary greatly and is thus another important consideration when choosing these devices.
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Hosp. Pract. (Off. Ed.) · Jun 1993
ReviewOutpatient parenteral antibiotic therapy. Management of serious infections. Part I: Medical, socioeconomic, and legal issues. Pediatric considerations.
Outpatient parenteral antibiotic therapy (OPAT) is less threatening to children than in-hospital treatment and most likely reduces the risk of nosocomial infection. Most pediatric infections can be treated in the home if patients are medically stable, parents are motivated to help with therapy, and appropriate resources, such as skilled pediatric nursing, are available. The cost of pediatric OPAT is similar to that of adult OPAT.
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Celiac sprue, also termed celiac disease or gluten-sensitive enteropathy, is a chronic disease in which malabsorption of nutrients is caused by a characteristic, but nonspecific, lesion of the small-intestinal mucosa. The lesion is produced, through unclear mechanisms, by protein constituents of some cereal grains. Exclusion of wheat gluten and rye, barley, and oat prolamins from the diet results in a prompt improvement in absorption, along with reversion, toward normal, of the associated small-intestinal lesion. ⋯ When, on the other hand, the mucosal lesion is limited to the duodenum and proximal jejunum, overt gastrointestinal symptoms and steatorrhea may be absent. In those patients, clinical manifestations, if present at all, may reflect malabsorption of only one or two substances, notably iron and folate, that normally are absorbed somewhat selectively by the proximal intestine. Arriving at the correct diagnosis in such cases may be quite challenging.