Journal of medicine
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Journal of medicine · Jan 1987
Lower esophageal sphincter pressure and gastroesophageal pressure gradients in excessively obese patients.
The purpose of the present study was to investigate the relationship of the gastroesophageal pressure gradient (GEPG) to lower esophageal sphincter pressure (LESP) in normal and in severely obese subjects. Eight lean volunteers with no clinical evidence of gastroesophageal reflux and eight asymptomatic severely obese patients (at least 80% over their ideal weight) underwent esophageal manometric studies with measurements of the LESP and GEPG in both inspiration and expiration. The LESP/GEPG ratio was also calculated in both inspiration and expiration. ⋯ None of the normal subjects exhibited acid sensitivity, but 6 of the 7 obese patients tested developed heartburn during acid infusion. In conclusion, the GEPG/LESP ratio in inspiration was greater than unity for obese patients inspite of normal LESP. Such a change in the ratio could facilitate reflux in obese patients.
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The authors condensed their knowledge of physical injuries of skeletal muscle, particularly injuries caused by mechanical energy, atmospheric pressure, radiation, extremes of temperature and electricity. The possible perils, outcomes and consequences are discussed. Special attention is given to the military medical projections.
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Journal of medicine · Jan 1983
Comparative StudyMinerals in blood sera and scalp hair in patients with lepromatous leprosy and tuberculoid leprosy.
Scalp hair and blood sera of three groups of individuals were studied for mineral contents by flame photometric and colorimetric procedures. Patients in one of the three groups were suffering from lepromatous leprosy, the second group comprised patients with tuberculoid leprosy and the third group consisted of normal controls. The results obtained revealed changes in the mineral content of the scalp hair of those suffering from lepromatous leprosy and tuberculoid leprosy. A possible relationship may exist between hair and serum minerals.
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Journal of medicine · Jan 1982
Comparative StudyUse of intrathecal and epidural morphine for pain relief in patients with malignant diseases: a preliminary report.
The results of a preliminary study involving the treatment of various malignant pain disorders by intrathecal (I. T.) or epidural (E) morphine sulfate (M. ⋯ The overall duration of pain relief was modest and ranged from 10 to 72 hours; the intrathecal route provided a slightly longer duration (median: 48 hours; range: 15-72 hours) of analgesia than that of the epidural route (median: 20 hours; range: 10-72 hours). Minor and transient complications occurred in 10 (55%) patients.
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Journal of medicine · Jan 1982
Case ReportsConcepts in the use of hypnosis for pain relief in cancer.
Hypnosis has no single place, but rather a broad range of application of technique and a long standing basis in the philosophy of patient care. We are not purists in any sense of the word. Our use of hypnosis in relief of pain in cases of cancer involves all formal medical procedures enhancing their potential through proper suggestions. We will endeavor to present some techniques of relaxation and pertinent case histories.