Pain medicine : the official journal of the American Academy of Pain Medicine
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Randomized Controlled Trial
Women with pain due to osteoarthritis: the efficacy and safety of a once-daily formulation of tramadol.
This analysis assesses the efficacy and safety of treatment with a once-daily oral formulation of tramadol for up to 12 weeks compared with placebo in women with moderate-to-severe pain due to osteoarthritis of the knee. ⋯ For moderate-to-severe pain due to osteoarthritis of the knee, women experience significant analgesia and improvement of physical function over time with treatment with Tramadol Contramid OAD.
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Chronic or recurrent nonmalignant pain is a significant problem for many children and adolescents and often limits the child's participation in normal physical, academic, and social activities. ⋯ The authors suggest that physicians and parents who take the initiative to elicit the child's narrative can help the child to rewrite the story to promote therapeutic change, a better outcome, and higher satisfaction.
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Review Meta Analysis
Quality of reporting of regional anesthesia outcomes in the literature.
Consistent and reliable standards for reporting of regional anesthetic adverse events are lacking. The quality of reporting of regional anesthetic morbidity has not been assessed critically. ⋯ Consistent and comparative regional anesthesia outcome data are lacking in peer-reviewed journals. A graded regional anesthetic morbidity and mortality system according to the intensity of therapy required for the treatment of the defined complication is proposed, along with a structured format for the reporting of regional anesthesia complications according to defined reporting standards.
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Randomized Controlled Trial
Intranasal ketorolac for postoperative pain: a phase 3, double-blind, randomized study.
Analgesic efficacy and tolerability of intranasal (IN) ketorolac was evaluated in postoperative patients in a randomized, double-blind, placebo-controlled study. ⋯ IN ketorolac was well tolerated and effective in treating moderate-to-severe postoperative pain in inpatients; the convenience of IN dosing suggests that its usefulness in the ambulatory care setting should be evaluated.
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Comparative Study
Risk for five forms of suicidality in acute pain patients and chronic pain patients vs pain-free community controls.
. The objective of this study was to determine the risk for five forms of suicidality in rehabilitation acute pain patients (APPs) and rehabilitation chronic pain patients (CPPs) vs pain-free community controls. ⋯ Rehabilitation CPPs are at greater risk for some forms of suicidality than community pain-free controls. This risk is increased by variables such as worker's compensation status, litigation status, and personal injury status. However, it is yet unclear if these variables actually predict suicidality as this requires further analysis.