Pain medicine : the official journal of the American Academy of Pain Medicine
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Review Meta Analysis
Effect of Continuous Local Anesthetic in Post-Cardiac Surgery Patients: A Systematic Review.
The purpose of this review was to determine the effect of CLA infusion post cardiac surgery on pain, time to ambulation, severe adverse events, patient satisfaction, time to extubation, length of stay in the intensive care unit and in the hospital, total narcotic consumption, and pulmonary function. ⋯ CLA infusion after cardiac surgery reduces pain score at 72 hours, shortens time to ambulation, and reduces morphine consumption at 48 hours.
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The hypotheses of this systematic review were the following: 1) Prevalence of post-traumatic stress disorder (PTSD) will differ between various types of chronic pain (CP), and 2) there will be consistent evidence that CP is associated with PTSD. ⋯ The results of this systematic review confirmed the hypotheses of this review.
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Review Meta Analysis
Sham Surgery in Orthopedics: A Systematic Review of the Literature.
To evaluate the evidence for the effectiveness of sham surgery in orthopedics by conducting a systematic review of literature. ⋯ This review suggests that sham surgery has shown to be just as effective as actual surgery in reducing pain and disability; however, care should be taken to generalize findings because of the limited number of studies.
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Review Meta Analysis
Ear Acupuncture for Immediate Pain Relief-A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
To systematically review the literature on the effectiveness of ear acupuncture (EA) for immediate pain relief. ⋯ Ear acupuncture may be a promising modality to be used for pain reduction within 48 hours, with a low side effect profile. Rigorous research is needed to establish definitive evidence of a clinically significant difference from controls or from other pain treatments.
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Meta Analysis
Efficacy and Safety of Tanezumab on Osteoarthritis Knee and Hip Pains: A Meta-Analysis of Randomized Controlled Trials.
To evaluate the efficacy and safety of tanezumab for management of osteoarthritis (OA) knee and hip pain. ⋯ Tanezumab vs placebo provides superior pain relief and improvement in physical function and PGA in knee and hip osteoarthritis patients and is generally well tolerated with acceptable AEs. Low-dose tanezumab (10 or 25 µg/kg and 2.5 mg) provides similar effectiveness in reducing pain and improving function and is associated with fewer AEs. The long-term safety of tanezumab on osteoarthritis knee and hip pain needs further investigation.