São Paulo medical journal = Revista paulista de medicina
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Oculo-auriculo-vertebral spectrum (OAVS) is considered to be a defect of embryogenesis involving structures originating from the first branchial arches. Our objective was to describe the clinical and cytogenetic findings from a sample of patients with the phenotype of OAVS. ⋯ We found a wide range of clinical characteristics among the patients with OAVS. Different chromosomal abnormalities and gestational expositions were also observed. Thus, our findings highlight the heterogeneity of the etiology of OAVS and the importance of these factors in the clinical and cytogenetic evaluation of these patients.
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Case Reports
Azacitidine and lenalidomide as an alternative treatment for refractory acute myeloid leukemia: a case report.
Refractory acute myeloid leukemia (AML) is a difficult disease to control with second or third-line chemotherapy regimens. In this report, we describe using azacitidine in combination with lenalidomide as salvage therapy. ⋯ Azacitidine plus lenalidomide can be a therapeutic option for patients with refractory AML, as illustrated in this case.