São Paulo medical journal = Revista paulista de medicina
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Syphilis is a major public health issue worldwide. In people living with human immunodeficiency virus (PLHIV), there are higher incidences of both syphilis and neurosyphilis. The criteria for referring PLHIV with syphilis for lumbar puncture is controversial, and the diagnosis of neurosyphilis is challenging. ⋯ This study highlights heterogeneities in the clinical management of HIV-syphilis coinfection. Most infectious disease specialists still consider syphilis stage, VDRL titers and CD4+ cell counts as important parameters when deciding which patients need lumbar puncture for investigating neurosyphilis.
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Increased longevity is accompanied by new social and health demands, such as the race/color social construct, indicating the need to identify the specific needs of older adults to maintain and improve their quality of life. ⋯ Factors associated with poorer self-assessed quality of life among older adults in the study community differed according to race/color.
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Randomized Controlled Trial
Compression pre-stapler firing and post-ignition wait during sleeve gastrectomy: a prospective randomized trial.
Insufficient research exists on the stapling technique in and duration of laparoscopic sleeve gastrectomy (LSG). ⋯ ClinicalTrials.gov with registration code NCT05703035; link: https://clinicaltrials.gov/ct2/show/NCT05703035.
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A bibliometric analysis covering only the production of original studies or considering world production until 2022 has yet to be conducted. The creation and advancement of vaccines have also influenced research priorities, demonstrating the need for a new approach to this subject. ⋯ Further research should be conducted, mainly concerning vaccines and vaccination of the aged, owing to the need for and importance of immunization in this risk group, including assessing the long-term effects of vaccines.
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The Pregnancy Mobility Index (PMI) was developed to assess mobility in pregnant women in the Netherlands. At present, no similar questionnaire is available in Brazil. ⋯ RBR-789tps (Validation study), https://ensaiosclinicos.gov.br/rg/RBR-789tps.