Sleep medicine
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Clinical Trial
Impact of sleeping position on central sleep apnea/Cheyne-Stokes respiration in patients with heart failure.
The present study determines the influence of sleeping position on central sleep apnea (CSA) in patients with heart failure (HF). ⋯ As cardiac dysfunction progresses, severity of CSA also increases and positional CSA becomes position-independent. Positional therapy could decrease CSA, thereby having a valuable effect on HF.
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The aim of this study was to examine the effects of extended work hours (10 h on, 14 h off for 21 days) on sleep and sleepiness in an extreme and isolated environment in the far north (Spitsbergen, 78 degrees north). We wanted to examine whether sleep duration, sleepiness and other parameters changed over the 3-week working period and whether the parameters differed between day and night shifts. ⋯ There were few differences between the day and night shift periods and across the 21-day working period, as measured both subjectively and objectively. The subjects experienced few problems and seemed to adapt easily to their work schedule. This contrasts with what is usually the case in more conventional shift work situations, where workers do not adapt well, as measured by sleepiness and various sleep parameters.
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Randomized Controlled Trial Multicenter Study
Efficacy and safety of pramipexole in Japanese patients with primary restless legs syndrome: A polysomnographic randomized, double-blind, placebo-controlled study.
To evaluate the efficacy of pramipexole on polysomnographic measures, patient ratings and a clinical rating in Japanese patients with primary restless legs syndrome (RLS). ⋯ Pramipexole is highly efficacious in the reduction of PLMI and in the improvement of subjective severity of RLS and subjective sleep disturbance caused by the disorder.
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(1) To quantify night-to-night variability in sleep behaviors and sleep measures among older chronic insomnia (CI) subjects and non-insomnia (NI) controls; (2) to investigate systematic temporal patterns of sleep behaviors and sleep measures across nights; and (3) to examine clinical correlates of sleep variability. ⋯ Compared to NI, older adults with CI report worse sleep and greater night-to-night variability, which was confirmed with actigraphy. There was little evidence for positive or negative correlation of sleep measures across nights. Variability of sleep may be an important target for insomnia treatments.
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The relationship between reports of insomnia and daytime functioning was investigated using hierarchical regression. The presence or absence of a report of insomnia was the predictor of primary interest. A number of covariates were included in the model: demographic variables, health variables, and quantitative sleep parameters. ⋯ Individuals' perceptions of their sleep are related to differences in their reported daytime functioning, which are not accounted for by demographic factors, health surveys, or quantitative sleep assessments. Reports of insomnia may be related to a set of common cognitive factors among individuals who report having insomnia which cause them to be distressed with their sleep and increase their dissatisfaction with daytime functioning. Relevance of the findings to insomnia research and clinical management are discussed.