Drug and therapeutics bulletin
-
In 1986, DTB published an article called Herbal medicines - safe and effective?, which discussed some of the issues around the availability, safety and efficacy of such treatments.1 We highlighted how the failure of orthodox medicines to cure, and anxiety about their potentially serious unwanted effects, had led some people to turn to herbal medicines for treatment for chronic and disabling conditions often in the belief, that natural medicines must be intrinsically safe. The article concluded by discussing the potential problems associated with herbal medicines and the role that doctors should play in asking about patients' use of such products. Revisiting these themes, here we present an overview of the results of an online survey conducted among DTB readers to explore four key issues: What do healthcare professionals know about herbal medicines? What challenges (if any) does patients' use of herbal medicines raise for healthcare professionals? What awareness do healthcare professionals have about the regulatory arrangements for herbal medicines? What sources of information (if any) do healthcare professionals use to inform themselves about herbal medicines?
-
The metal silver is well known to have antimicrobial properties and this underlies its incorporation into the many types of silver releasing wound dressings available in the UK. These products are classed as 'advanced' dressings and were developed primarily for difficult to heal wounds, chronic ulcers and extensive burns.1 The use of silver dressings has increased rapidly in recent years in the UK, with the amount spent on such products in the NHS being around pound23million in 2005 and around pound25million in 2006/7.2(,)3 The latter figure represents a quarter of the total cost of wound dressings, with one seventh of the wound dressing items prescribed being silver dressings.3 Here we discuss the evidence on the place of silver dressings in burns, chronic ulcers and acute wounds.
-
For many drugs, it is important to adjust the dose for individual patients. To estimate the dose, a patient's body weight or body surface area (BSA) is often used. BSA is difficult to measure directly, but may be calculated using formulae involving the patient's weight and height. Here we discuss BSA and when it is used in practice, in particular, for calculating drug doses in children and for cancer chemotherapy.
-
Generalised anxiety disorder (GAD) is common, with a prevalence of around 4% among adults in the UK. The condition is characterised by chronic excessive anxiety and worry, in combination with a variety of psychological or somatic symptoms. ⋯ Pregabalin (Lyrica - Pfizer) is a medicine licensed for GAD in adults. Here we review its role in the management of patients with the problem.