Boletín médico del Hospital Infantil de México
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Bol Med Hosp Infant Mex · Jan 1978
Comparative Study[Salicylate poisoning. Determination of the free fraction using the ultrafiltration method].
Seventeen infants under one year of age admitted to the Emergency Service of the General Hospital of the Medical Center La Raza during the year 1976 were included in this study with the diagnosis of salicylate poisoning. Determination of plasma salicylate by the ultrafiltrate method was practiced to all patients. A direct relationship between total plasmatic salicylate and its free fraction was found together with an inverse proportion between percentage of total free--salicylate and plasma pH and a lineal correlation between plasma free--salicylate and salicylate obtained in spinal fluid. It is concluded that determination of the free fraction of plasma salicylate is an easy diagnostic method for the better evaluation of salicylate acid poisoning in the infant.
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Bol Med Hosp Infant Mex · Mar 1977
[What is wrong with the measles vaccine in Mexico? Study of an epidemic outbrake of measles].
The study included 205 children with measles seen after an epidemic outbreak in Distrito Federal during the first six months of 1976. 65.8% of the cases had not been given specific immunization and out of the 70 vaccinated cases (34.2%), one half of them were under one year old and were not given re-enforcement afterwards. The clinical picture suffered no changes in vaccinated children, 40% of infants showed initial exanthema on chest and abdomen with centrifugal distribution and in 41.5% of them, diarrhea appeared during the prodromal period. The most outstanding elements of this epidemic outbreak were the high number of sensible cases and the high percentage of children vaccinated before the age of one year and who were not later given re-vaccination. Indequate handling of the vaccine or combination of vaccine withe gammaglobulin used in 1969 and 1970, are also mentioned as a possibility to explain failures of the vaccine in ths group of well vaccinated children.
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Bol Med Hosp Infant Mex · May 1975
Comparative Study[Comparison between the 3- and the 24-hour urine collection for creatinine clearance].
Endogenous creatinine clearance was studied in thirty children with various renal diseases and variable degrees of functional deterioration. Two different procedures or urine collection were used on each child: 1) twenty-four-hour urine collection with one blood sample and immediately afterwards 2) three one-hour consecutive periods of urine collection, with one previous blood sample (the one used for the 24-hour procedure). ⋯ The results obtained with both procedures did not show significant difference. The three-hour periods procedure may be recommended for hospitalized patients, specially infants or young children, and also when the parents are not reliable enough for hydrating the patients and for performing a complete collection of urine in a 24 hour period.