Pain physician
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Normal sacroiliac (SI) joints vary widely in shape, and it is unclear whether SI joint morphology plays a role in the development of pain. To answer this question, we used 3D-CT surface rendering to image healthy study participants and used the resulting images to develop a classification system for SI joint morphology. In a case-control study comparing health research participants to patients with SI pain, we assessed whether the classification of SI joint morphology was associated with pain. ⋯ Sacroiliac joint, spine pain, 3D reformation, SI joint area, SI joint shape, SI joint pain syndrome.
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Review Meta Analysis
Efficacy of Palmitoylethanolamide for Pain: A Meta-Analysis.
Palmitoylethanolamide (PEA) is a cannabimimetic compound that has been investigated as an analgesic agent in animal models and clinical trials. ⋯ PEA, palmidrol, palmitoylethanolamide, efficacy, pain, pain management, meta-analysis.
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Refractive surgery is a common procedure, but may be associated with severe post-operative pain. ⋯ Photorefractive keratectomy, in situ keratomileusis, pain, analgesia, opioid, codeine, review.
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Research into interventional techniques in managing chronic spinal pain continues to be challenging, mystifying, confusing, and biased. Insight, or lack thereof, into placebo and nocebo phenomena contributes mightily to these difficulties. Unfortunately, placebo-nocebo responses are the subject of numerous controversies and challenges from not only a research perspective, but also clinical perspective. ⋯ This review focuses on a multitude of controversies surrounding placebo and nocebo phenomena in research and clinical applications. The discussion includes a focus on unsolved, forgotten, and ignored features of placebo responses in medicine, and provides an appropriate understanding of placebo and nocebo phenomena in interventional pain management. To that effect, this review also describes therapeutic placebos, research with open placebos, and improvements in understanding clinical applications of present interventional pain management research.