Pain physician
-
Several studies in recent years have confirmed that the direct application of pulsed radiofrequency (PRF) on peripheral nerve compression points can alleviate hyperalgesia in animal models of neuropathic pain (NP). However, the mechanism underlying the treatment of peripheral nerves by PRF is unclear. ⋯ Pulsed radiofrequency, chronic constriction injury, sciatic nerve, 50% paw withdrawal threshold, thermal withdrawal latency, glia cell line-derived neurotrophic factor, reverse transcription-polymerase chain reaction, enzyme-linked immunosorbent assay.
-
Meta Analysis
Fusion or Not for Degenerative Lumbar Spinal Stenosis: A Meta-Analysis and Systematic Review.
Degenerative lumbar spinal stenosis (DLSS) is the main cause for chronic low back pain in the elderly. When refractory to conservative treatment, symptomatic patients commonly undergo surgery. However, whether or not fusion is a relatively better surgical option still remains unclear. ⋯ Decompression, fusion, lumbar spinal stenosis, meta-analysis.
-
Meta Analysis
Efficacy of Pain Relief in Different Postherpetic Neuralgia Therapies: A Network Meta-Analysis.
Postherpetic neuralgia (PHN) is a nerve pain disease usually controlled by different therapies, i.e., topical therapies, antiepileptics, analgesics, antipsychotics, antidepressants, anti-dementia drugs, antivirals, amitriptyline, fluphenazine, and magnesium sulfate. It is believed that different therapies may lead to different levels of pain relief. ⋯ Postherpetic neuralgia, topical agents, antiepileptics, analgesics, antipsychotics, antidepressants.