Pain physician
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A previous study revealed elevated serum Immunoglobulin E (IgE) in ketamine related cystitis (KC) patients. IgE might participate the pathogenesis of different types of bladder pain syndromes, including KC and interstitial cystitis (IC). ⋯ Immunoglobulin E, ketamine cystitis, interstitial cystitis.
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Chemotherapy-induced neuropathic pain is difficult to treat. Pentoxifylline inhibits the production of inflammatory cytokines including tumor necrosis factor α(TNF- α) and interleukin 1β (IL-1β). ⋯ Pentoxifylline alleviated chemotherapy-induced neuropathic pain in rats by reducing the levels of inflammatory cytokines in dorsal root ganglia and may be effective chemotherapy-induced neuropathic pain in patients.
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Biography Historical Article
In Memoriam of an Eminent Pain Physician: Phulchand Prithvi Raj.
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Review Meta Analysis
Local Infiltration Analgesia Versus Regional Blockade for Postoperative Analgesia in Total Knee Arthroplasty: A Meta-analysis of Randomized Controlled Trials.
Total knee arthroplasty (TKA) is one of the most commonly performed procedures while postoperative analgesia still remains challenging. The efficacy and safety of local infiltration analgesia (LIA) versus regional blockade (RB; epidural analgesia and/or peripheral nerve block) for pain management after TKA are controversial. ⋯ Local infiltration analgesia, regional block, peripheral nerve block, epidural analgesia, postoperative analgesia, total knee arthroplasty, meta-analysis, randomized controlled trial.