Archivum immunologiae et therapiae experimentalis
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Arch. Immunol. Ther. Exp. (Warsz.) · Jan 1977
Comparative Study Clinical Trial Controlled Clinical TrialA double-blind comparative evaluation of aspirin, paracetamol and paracetamol + caffeine (finimal) for their analgesic effectiveness.
A double-blind, cross-over trial was made of three analgesic preparations--paracetamol, paracetamol with caffeine (Finimal) and aspirin in the relief of postoperative pain in 72 orthopedic inpatients and in 144 ambulatory outpatients suffering form common idiopathic headache. The combination of paracetamol and caffeine (Finimal) in this study shows the greatest pain relief in both groups of patients. This evaluation supports the results of BOOY3 demonstrating the superiority of the paracetamol-caffeine combination to paracetamol alone or aspirin.
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Arch. Immunol. Ther. Exp. (Warsz.) · Jan 1976
Population shift in drug resistant and sensitive Escherichia coli during antibiotic treatment of children with diarrhea.
Changes in composition of Escherichia coli were followed during antibiotic therapy of nin children with acute diarrhea. In five cases enteropathogenic serotypes of E. coli were multiple-drug resistant, and in four other this feature characterized nonpathogenic E. coli strains. The results point to the importance of choice of the drugs effective not only against pathogenic serotypes, but also against nonpathogenic ones, and uselessness and even harmfulness of chemotherapy "in blindly".