The lancet oncology
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The lancet oncology · Jul 2022
Screening and eradication of Helicobacter pylori to prevent gastric cancer in indigenous Taiwanese communities: a population-based study and development of an index-case method.
Gastric cancer is one of the leading causes of cancer death, particularly in Asia and South America. Screening and eradication of Helicobacter pylori is recognised as an advantageous solution to reduce the disparities in the incidence of this cancer. However, the deployment of such policies is not yet sufficiently advanced in high-incidence areas. Our study aimed to show the acceptability and feasibility of an index-case method to implement a screening and eradication policy in high-risk populations living in Taiwanese indigenous communities. ⋯ Health Promotion Administration, Ministry of Health and Welfare, Taiwan (grant number A1101008).
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The lancet oncology · Jul 2022
Observational StudyColorectal cancer trends in Chile: an observational study.
Colorectal cancer is the third most frequent malignant disease worldwide. In Chile, colorectal cancer has been part of the Garantías Explícitas en Salud (Explicit Guarantees in Health Programme; also known as GES), which aims to ensure prompt access to affordable and quality health care, since 2014. Survival depends on the diagnosis of the disease in the earliest possible stage and on rapid access to adequate treatment. However, extreme inequality in social factors, such as education and income, has resulted in poor outcomes in cancer survival. The aim of this study was to obtain data on the epidemiology of colorectal cancer in Chile (in 2009-18) and on the effect of measurable factors on survival. ⋯ Complex Engineering Systems Institute (Centro Basal ANID/AFB18003) and Agencia Nacional de Investigación y Desarrollo/Programa de Becas/Doctorado Nacional 21200869.
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The lancet oncology · Jul 2022
Observational StudySalivary and tumour tissue miR-21 for prediction of cervical lymph node metastasis in patients with oral squamous cell carcinoma: an observational study.
Oral squamous cell carcinoma is a substantial health burden and one of the most common cancers worldwide. 40% of patients with oral squamous cell carcinoma have metastasis to cervical lymph nodes. Modern diagnostic aids for the assessment of lymph node metastasis have some limitations and drawbacks. miR-21 targets genes associated with the metastatic process in oral squamous cell carcinoma. The aim of the study was to evaluate the sensitivity and specificity of miR-21 for the assessment of cervical lymph node metastasis in patients with oral squamous cell carcinoma. ⋯ None.
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The lancet oncology · Jul 2022
Excess mortality in patients with cancer during the COVID-19 pandemic in Peru: an analysis of death registry data.
The COVID-19 pandemic has had a direct effect on patients with cancer, as reflected by the large number of COVID-19-related cancer deaths reported worldwide and the substantial decrease in cancer-related consultations during the pandemic. However, the impact of the COVID-19 pandemic on cancer mortality in Latin American countries has not been properly estimated. The aim of this study was to analyse the excess mortality related to cancer during the pandemic in Peru, including deaths directly or indirectly attributed to COVID-19. ⋯ International Joint Laboratories Programme of the French National Research Institute for Sustainable Development.