The lancet oncology
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The lancet oncology · Dec 2014
ReviewEpidemiology, biology, and treatment of triple-negative breast cancer in women of African ancestry.
Breast cancer incidence is increasing worldwide, and breast cancer-related mortality is highest in women of African ancestry, who are more likely to have basal-like or triple-negative breast cancer (TNBC) than are women of European ancestry. Identification of cultural, epidemiological, and genetic risk factors that predispose women of African ancestry to TNBC is an active area of research. ⋯ First, we summarise the existing published work on the differences reported on the epidemiology, biology, and response to systemic treatment of TNBC between women of African ancestry and white women, and identify some gaps in knowledge. Second, we review the opportunities for development of new therapeutic agents in view of the potential high clinical relevance for patients with TNBC irrespective of race or ethnic origin.
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The lancet oncology · Dec 2014
Practice GuidelineGlobal uptake of BHGI guidelines for breast cancer.