The lancet oncology
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The lancet oncology · Sep 2012
Review Meta AnalysisOvarian cancer and smoking: individual participant meta-analysis including 28,114 women with ovarian cancer from 51 epidemiological studies.
Smoking has been linked to mucinous ovarian cancer, but its effects on other ovarian cancer subtypes and on overall ovarian cancer risk are unclear, and the findings from most studies with relevant data are unpublished. To assess these associations, we review the published and unpublished evidence. ⋯ Cancer Research UK and MRC.
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The lancet oncology · Sep 2012
Randomized Controlled Trial Multicenter Study Comparative StudyTemozolomide versus standard 6-week radiotherapy versus hypofractionated radiotherapy in patients older than 60 years with glioblastoma: the Nordic randomised, phase 3 trial.
Most patients with glioblastoma are older than 60 years, but treatment guidelines are based on trials in patients aged only up to 70 years. We did a randomised trial to assess the optimum palliative treatment in patients aged 60 years and older with glioblastoma. ⋯ Merck, Lion's Cancer Research Foundation, University of Umeå, and the Swedish Cancer Society.