The lancet oncology
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The lancet oncology · Jun 2023
Multicenter StudyRadical cystectomy versus trimodality therapy for muscle-invasive bladder cancer: a multi-institutional propensity score matched and weighted analysis.
Previous randomised controlled trials comparing bladder preservation with radical cystectomy for muscle-invasive bladder cancer closed due to insufficient accrual. Given that no further trials are foreseen, we aimed to use propensity scores to compare trimodality therapy (maximal transurethral resection of bladder tumour followed by concurrent chemoradiation) with radical cystectomy. ⋯ Sinai Health Foundation, Princess Margaret Cancer Foundation, Massachusetts General Hospital.
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The lancet oncology · Jun 2023
Multicenter StudyThe prognosis of patients with small cell carcinoma of the cervix: a retrospective study of the SEER database and a Chinese multicentre registry.
Small cell carcinoma of the cervix is a rare but poor prognosis pathological type of cervical cancer, for which advice in clinical guidelines is unspecific. We therefore aimed to investigate the factors and treatment methods that affect the prognosis of patients with small cell carcinoma of the cervix. ⋯ The National Key R&D Program of China and the National Natural Science Foundation of China.
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The lancet oncology · Jun 2023
Global funding for cancer research between 2016 and 2020: a content analysis of public and philanthropic investments.
Cancer is a leading cause of disease burden globally, with more than 19·3 million cases and 10 million deaths recorded in 2020. Research is crucial to understanding the determinants of cancer and the effects of interventions, and to improving outcomes. We aimed to analyse global patterns of public and philanthropic investment in cancer research. ⋯ None.